Tiny robots, big impact: Revolutionizing infertility treatment with magnetic microrobots

“This new technology provides a potentially less invasive alternative to the traditional surgical methods currently used to clear fallopian tube blockages, which often require the use of traditional catheters and guidewires,” said author Xu Haifeng.

The microrobot is made from non-magnetic photosensitive resin and coated with a thin layer of iron to give it magnetism. By applying an external magnetic field, the robot rotates, creating a translational motion that allows it to pass through a glass channel that simulates the fallopian tube. The robot successfully cleared cell cluster obstacles in the channel and simulated typical obstacles of the female reproductive system. This magnetic control allows precise navigation of the delicate and narrow structures of the fallopian tube.

The design of microrobots is another key innovation. It has a spiral body, a cylindrical central tube, and a disc-shaped tail. The spiral structure is crucial for propulsion, while the disc-shaped tail helps stabilize the robot’s movement. As the screw rotates, it creates a vortex field that helps push debris toward the rear, clearing blockages more efficiently.

In tests, the microrobot demonstrated its effectiveness and efficiency in clearing simulated clogs, with the vortex created by the rotating screw pushing debris away from the obstruction.

Looking to the future, the research team plans to make the microrobots smaller and more advanced. They also aim to test the robots in isolated organ models and incorporate in vivo imaging systems to instantly track the microrobot’s movement and position. The team also envisions expanding the use of robots in surgery, including automated control systems that could improve the efficiency of obstruction removal and other medical procedures.

“The ultimate goal is to provide more effective, minimally invasive solutions for infertility patients,” Xu said.